Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
azelaic acid + tretinoin
- Development stage
- Unknown
- Lead developer
- La Pristine Bioceuticals
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Xtralite is a topical combination cream containing azelaic acid and tretinoin, developed by La Pristine Bioceuticals. It is primarily indicated for the treatment of melasma, hyperpigmentation, and acne. Azelaic acid acts as a competitive inhibitor of tyrosinase, reducing melanin synthesis in hyperactive melanocytes, and also exhibits anti-inflammatory and antibacterial properties against Cutibacterium acnes. Tretinoin, a retinoid, binds to and activates retinoic acid receptors (RARs), promoting rapid skin cell turnover and epidermal renewal. Together, these active ingredients work synergistically to fade dark spots, improve skin texture, and clear blemishes.
- Brand names
- XtraliteXtralite Mild
- Other names
- azelaic acid + tretinointretinoin + azelaic acid
02
Targets
RARA (Retinoic acid receptor alpha)RARB (Retinoic acid receptor beta)RARG (Retinoic acid receptor gamma)TYR (Tyrosinase)
Beyond the preview
Go deeper on azelaic acid + tretinoin.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on azelaic acid + tretinoin.