Drug intelligence / Profile preview

Azyr Mega

Development stage
Unknown
Lead developer
Yield10 Bioscience
Modality
Small Molecules
Administration
Oral
01

Overview

Azyr Mega is a nutraceutical supplement formulation containing omega-3 fatty acids (DHA and EPA) combined with the AREDS2 formula components, which include lutein, zeaxanthin, astaxanthin, vitamin C, vitamin E, zinc, and copper. It was investigated by the Università degli Studi di Brescia in a Phase 4 randomized clinical trial (NCT03355638) as an adjunctive therapy to intravitreal aflibercept (Eylea) for the treatment of neovascular (exudative) age-related macular degeneration (nAMD). The supplement is designed to provide antioxidant and anti-inflammatory support to the retina, aiming to mitigate oxidative stress and inflammation associated with choroidal neovascularization. Clinical results indicated that patients receiving Azyr Mega in combination with aflibercept required significantly fewer anti-VEGF injections over a 12-month period compared to those receiving aflibercept monotherapy.

Brand names
Azyr Mega
Other names
Omega-3 SupplementationOmega3 SupplementationOmega 3 SupplementationAREDS2 formula plus omega-3AREDS-2 formula plus omega-3AREDS 2 formula plus omega-3
02

Targets

COX

Beyond the preview

Go deeper on Azyr Mega.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Azyr Mega.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call