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B-New
- Development stage
- Preclinical
- Lead developer
- JW Pharmaceutical
- Modality
- Small Molecules
01
Overview
B-New is a preclinical-stage small molecule inhibitor targeting the Signal Transducer and Activator of Transcription 3 (STAT3), developed by JW C&C Research Lab. STAT3 is a transcription factor that plays a pivotal role in oncogenesis by regulating the expression of genes involved in cell cycle progression, apoptosis resistance, and angiogenesis. It is frequently overactivated in a wide range of solid tumors and is also implicated in inflammatory diseases. The B-New program leverages JW C&C's proprietary CLOVER drug discovery platform to develop potent and selective inhibitors that can effectively block STAT3-mediated gene transcription, offering a potential therapeutic approach for cancers that are often resistant to conventional therapies.
- Other names
- B-New (STAT3)JW C&C STAT3 inhibitor
02
Targets
STAT3 (Signal Transducer and Activator of Transcription 3)
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