Drug intelligence / Profile preview

B1

Development stage
Phase 3
Lead developer
BOL Pharma
Modality
Small Molecules
Administration
Sublingual
01

Overview

B1 is a pharmaceutical-grade sublingual tablet formulation of a plant-derived cannabis extract developed by Breath of Life International Pharma Ltd (BOL Pharma). Each tablet contains a specific ratio of cannabinoids, specifically 40 mg of cannabidiol (CBD) and 2 mg of delta-9-tetrahydrocannabinol (THC). B1 is being evaluated for its safety and pharmacokinetic profile in Phase 1 clinical trials, with intended applications in treating neurodevelopmental and chronic pain conditions, including autism spectrum disorder (ASD) and neuropathic pain. The therapeutic effect is mediated through the modulation of the endocannabinoid system, where THC acts as a partial agonist at CB1 and CB2 receptors, and CBD interacts with various non-cannabinoid targets such as 5-HT1A receptors and GPR55, providing potential anti-inflammatory, analgesic, and behavioral-modulating effects.

Other names
CBD 40 mg + THC 2 mg sublingual tabletBOL-B1BOL-B-1BOL-B 1Breath of Life B1
02

Targets

HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))CNR1 (Cannabinoid receptor 1)FAAHGPR55 (G protein-coupled receptor 55)

Beyond the preview

Go deeper on B1.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on B1.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call