Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
B7H3-IL7Ra CAR-T cells
- Development stage
- Phase 1
- Lead developer
- Chulalongkorn University
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous, Intrathecal, Intracerebroventricular, Intratumoral
01
Overview
B7H3-IL7Ra CAR-T cells are a type of chimeric antigen receptor T-cell therapy designed to target the B7-H3 antigen, which is overexpressed on various solid tumors. These cells incorporate interleukin-7 receptor alpha (IL7Ra) signaling to enhance T-cell activation and proliferation. The therapy aims to improve the effectiveness of CAR-T cell treatment for solid tumors by maintaining T-cell function and reducing activation-induced cell death. It is being explored for use in cancers such as glioblastoma and diffuse intrinsic pontine glioma (DIPG).
- Other names
- B7H3 With IL-7 Receptor Alpha Signaling Chimeric Antigen Receptor T CellB-7H3 With IL-7 Receptor Alpha Signaling Chimeric Antigen Receptor T CellB 7H3 With IL-7 Receptor Alpha Signaling Chimeric Antigen Receptor T CellB7H3 specific CAR T cell with IL-7Ra signaling domainB-7H3 specific CAR T cell with IL-7Ra signaling domainB 7H3 specific CAR T cell with IL-7Ra signaling domain
02
Targets
B7-H3
Beyond the preview
Go deeper on B7H3-IL7Ra CAR-T cells.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on B7H3-IL7Ra CAR-T cells.