Drug intelligence / Profile preview

BA301

Development stage
Preclinical
Lead developer
T-Cypher Bio
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

BA301 is a bispecific T-cell engager (TCE) being developed by T-Cypher Bio for the treatment of various autoimmune diseases. The therapeutic candidate is designed to target TC301, a specific antigen, and simultaneously bind to the CD3 receptor on T cells to redirect their activity. In the context of autoimmune therapy, this mechanism is typically intended to deplete pathogenic cell populations, such as autoreactive B cells or T cells, that drive disease pathology. BA301 is currently in the discovery and lead selection phase of development.

02

Targets

BlaR (Beta-lactamase regulatory protein BlaR)CD3 (T-cell surface glycoprotein CD3)

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