Bacillus coagulans SANK70258

Bacillus coagulans SANK70258 (marketed under the brand name Lacbon) is a spore-forming, lactic acid-producing probiotic bacterium originally isolated from green malt in 1949 by Dr. Oki Nakayama and developed by Sankyo (now Daiichi Sankyo Healthcare). Unlike conventional lactic acid bacteria, B. coagulans SANK70258 forms highly stable endospores that exhibit remarkable resistance to heat and gastric acid, allowing them to survive passage through the stomach and reach the intestines alive. Once in the intestinal tract, the spores germinate into active vegetative cells that produce L(+)-lactic acid, suppress the growth of harmful putrefactive bacteria (such as Enterobacteriaceae), and promote a healthy gut microbiota. It is approved in Japan for regulating bowel movements and improving symptoms of constipation, loose stools, and abdominal bloating, and is marketed in OTC formulations such as Panlacmin Tablets.

Brand names

Lacbon

Other names

Bacillus coagulans SANK 70258Bacillus coagulans SANK70258Heyndrickxia coagulans SANK 70258Heyndrickxia coagulans SANK70258Lactobacillus sporogenesWeizmannia coagulans SANK 70258Weizmannia coagulans SANK70258中山氏有胞子性乳酸菌有胞子性乳酸菌ラクボン