Drug intelligence / Profile preview

Bacillus coagulans TCI711

Development stage
Preclinical
Lead developer
TCI
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bacillus coagulans TCI711 is a specific probiotic strain of the Gram-positive, spore-forming bacterium *Bacillus coagulans*, originally isolated from apples. Developed by TCI Co., Ltd., this strain is characterized by its ability to produce lactic acid and its high stability against heat, acid, and bile, allowing it to survive transit through the gastrointestinal tract. It is being investigated for its potential to enhance alcohol metabolism (alcohol elimination) and to improve liver function and gut microbiota composition in patients with non-alcoholic fatty liver disease (NAFLD). The strain's mechanism likely involves modulation of the intestinal microbiome and metabolic pathways related to ethanol and lipid processing.

Other names
Bacillus coagulans TCI711

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