Drug intelligence / Profile preview

bacillus subtilis BS50

Development stage
Unknown
Lead developer
BIO-CAT Microbials
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bacillus subtilis BS50 is a proprietary, spore-forming probiotic strain developed by BIO-CAT Microbials. Characterized by its robust heat resistance and pH tolerance, the strain is designed to survive the acidic environment of the human stomach to reach the intestines. BS50 has been shown to secrete digestive enzymes and microbiota-modulating molecules that support gastrointestinal function. In clinical studies, daily supplementation with 2x10⁹ CFU of BS50 significantly improved gas-related symptoms, including abdominal bloating, flatulence, and burping, in healthy adults. Preclinical genomic analysis has confirmed the safety profile of the strain, demonstrating an absence of known Bacillus toxins and virulence factors.

Other names
Bacillus subtilis BS50
02

Targets

LCT (Lactase-phlorizin hydrolase)

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