Drug intelligence / Profile preview

bacitracin zinc + hydrocortisone + lidocaine + neomycin sulfate + polymyxin b sulfate

Development stage
Unknown
Lead developer
CND Pharma
Modality
Small Molecules
Administration
Topical
01

Overview

Cortracin-L is a topical combination medication developed and marketed by CND Pharma. It is a multi-ingredient formulation containing three antibiotics (bacitracin zinc, neomycin sulfate, and polymyxin b sulfate), a corticosteroid (hydrocortisone), and a local anesthetic (lidocaine). This combination is designed to treat minor skin infections while simultaneously reducing inflammation, itching, and providing temporary relief from pain. The antibiotic components provide broad-spectrum coverage against Gram-positive and Gram-negative bacteria by inhibiting cell wall synthesis (bacitracin), disrupting protein synthesis (neomycin), and altering cell membrane permeability (polymyxin B). Hydrocortisone acts as an anti-inflammatory agent by suppressing the immune response, while lidocaine provides analgesic effects by blocking voltage-gated sodium channels in nerve fibers. It is typically used for the prevention and treatment of infections in minor cuts, scrapes, and burns.

Brand names
Cortracin-L
Other names
Cortracin-L
02

Targets

C55-PP (Undecaprenyl pyrophosphate)Bacterial RibosomeGR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)

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