Drug intelligence / Profile preview

bacitracin zinc + polymyxin b sulfate + hydrocortisone + neomycin

Development stage
Unknown
Lead developer
Bausch + Lomb
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

**bacitracin zinc + polymyxin b sulfate + hydrocortisone + neomycin** is a topical ophthalmic combination product containing three antibacterial agents and one corticosteroid. Neomycin and polymyxin B provide broad-spectrum antibacterial activity, bacitracin adds additional Gram-positive antibacterial coverage, and hydrocortisone reduces ocular inflammation through glucocorticoid receptor-mediated anti-inflammatory effects. The ointment is indicated for steroid-responsive inflammatory ocular conditions in which a corticosteroid is indicated and there is bacterial infection or risk of bacterial infection, including inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe, as well as chronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns or penetration of foreign bodies. It is marketed as a generic ophthalmic ointment by multiple manufacturers rather than a single originator company.

Other names
neomycin and polymyxin b sulfates, bacitracin zinc, and hydrocortisone ophthalmic ointmentneomycin and polymyxin b sulfates, bacitracin zinc, and hydrocortisone ophthalmic ointment uspbacitracin zinc + polymyxin b sulfate + hydrocortisone + neomycin ophthalmic ointment
02

Targets

UppP (Undecaprenyl pyrophosphate phosphatase)GR (Glucocorticoid receptor)Bacterial Ribosome

Beyond the preview

Go deeper on bacitracin zinc + polymyxin b sulfate + hydrocortisone + neomycin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on bacitracin zinc + polymyxin b sulfate + hydrocortisone + neomycin.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call