Drug intelligence / Profile preview

bacolin

Development stage: Unknown
Lead developer: Institute of Materia Medica, Chinese Academy of Medical Sciences
Modality: Small Molecules
Administration: Oral

Overview

Bacolin is a small molecule drug candidate developed by the Institute of Materia Medica, Chinese Academy of Medical Sciences (IMM CAMS) for the treatment of Parkinson's disease. Classified as a Class 1.1 innovative drug in China, Bacolin is a flavonoid derivative designed to target multiple pathological pathways of the disease. Its primary mechanism of action involves the inhibition of alpha-synuclein aggregation, which is a hallmark of Parkinson's disease pathology. Additionally, it demonstrates neuroprotective effects through antioxidant and anti-inflammatory activities. Bacolin is currently in Phase 1 clinical development, with studies focusing on its safety, tolerability, and pharmacokinetic profile in healthy volunteers and elderly populations in China.

Other names: 巴考林

Targets

aggregated α-syn (Alpha-synuclein (α-syn))

Beyond the preview

Go deeper on bacolin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on bacolin.

Explore the full profile