Drug intelligence / Profile preview

bacopa monnieri

Development stage
Phase 2
Modality
Drug Delivery Systems
Administration
Oral
01

Overview

Bacopa monnieri is a creeping perennial plant in the Scrophulariaceae family, native to wetlands in Southern India, Australia, and parts of Asia. It has small oblong leaves and white to purple flowers. Historically used in traditional Ayurvedic medicine, it is primarily known for its cognitive-enhancing properties, memory improvement, and also for conditions like insomnia, epilepsy, and as an anxiolytic (anti-anxiety agent). The active components are primarily triterpenoid saponins known as **bacosides**, which are thought to be responsible for its pharmacological actions. Research suggests these bacosides may protect nerve cells, improve learning and memory (including spatial learning, information retention, verbal learning, and delayed word recall), increase dendritic length and branching in nerve cells, and reduce anxiety. Additionally, studies suggest it may have anti-inflammatory properties by suppressing pro-inflammatory cytokines and inhibiting enzymes involved in inflammation and pain. Potential neurological benefits include antidepressant and antiepileptic effects. It is generally considered well-tolerated, with common side effects being gastrointestinal issues like increased stool frequency, nausea, and abdominal cramps. It is widely available as an over-the-counter dietary supplement.

Brand names
CDRI-08CDRI08CDRI 08KeenMind
Other names
BrahmiJalanimbaJalnaveriSambrani chettuThyme-leaved gratiola
02

Targets

CYP3A4 (Cytochrome P450 3A4)DNA gyraseMAOB (Monoamine oxidase B)CYP2D6 (Cytochrome P450 2D6)MAOA (Monoamine oxidase A)STXBP1 (Syntaxin-binding protein 1)CASP3 (Caspase-3)

Beyond the preview

Go deeper on bacopa monnieri.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on bacopa monnieri.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call