Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Bacteroides cocktail
- Development stage
- Discontinued
- Lead developer
- Baylor College of Medicine
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral, Rectal
01
Overview
The Bacteroides cocktail is an investigational live biotherapeutic product developed by Baylor College of Medicine for the treatment of recurrent *Clostridioides difficile* infection (rCDI). Unlike conventional fecal microbiota transplantation (FMT), which utilizes screened donor stool, this product consists of a defined, standardized mixture of cultured *Bacteroides* species. The therapy is designed to restore the ecological balance of the intestinal microbiome and provide colonization resistance against *C. difficile* by outcompeting the pathogen for nutrients and niches. A Phase 1 clinical trial was conducted in Veterans Affairs (VA) patients to evaluate the safety and efficacy of the cocktail administered via oral capsules or colonoscopy; however, the study was terminated due to challenges in patient recruitment and manufacturing the defined bacterial mixture to required standards.
- Other names
- Defined FMTDefined Fecal Microbiota TransplantBacteroides cocktail
Beyond the preview
Go deeper on Bacteroides cocktail.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Bacteroides cocktail.