Drug intelligence / Profile preview

bael leaf

Development stage
Unknown
Modality
Small Molecules
Administration
Oral (decoction/tea/powder), Topical (paste/oil)
01

Overview

Bael leaf refers to the leaves of the *Aegle marmelos* tree (commonly known as bael), a plant native to Southeast Asia and widely used in traditional medicine systems such as Ayurveda. Bael leaves are rich in bioactive compounds including tannins, aegeline, skimmianine, cineol, and eugenol. Traditionally used for their anti-inflammatory, antibacterial, antifungal, antioxidant and mild laxative properties[2][4][5][6], bael leaves are employed to support digestive health (treating constipation and dyspepsia), manage diarrhea and dysentery (as an astringent), soothe inflamed skin or rashes[2], promote wound healing[6], relieve coughs (as an expectorant)[5], and potentially lower blood sugar levels[1][3]. Extracts from the leaves have also shown radioprotective effects in laboratory studies by scavenging free radicals[4]. The main mechanism of action is attributed to tannins that reduce inflammation in the gut mucosa; other phytochemicals may contribute antimicrobial or immunomodulatory effects. Bael leaves are not approved pharmaceuticals but are widely used as dietary supplements or herbal remedies.

Other names
Aegle marmelos leafBilva leafBel leafBengal quince leafIndian bael leafWood apple leaf
02

Targets

PGN (Peptidoglycan)Cyp (Cyclophilin family)mAChR (Muscarinic acetylcholine receptors)

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