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bai tou weng decoction + ku shen decoction
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Rectal
01
Overview
Bai Tou Weng decoction + Ku Shen decoction is a Traditional Chinese Medicine (TCM) herbal combination therapy primarily utilized as a retention enema for the treatment of chronic ulcerative colitis. The formulation is a combination of two traditional decoctions: Bai Tou Weng Tang (centered on *Pulsatilla chinensis* root) and Ku Shen Tang (centered on *Sophora flavescens* root). In TCM pharmacology, these herbs are recognized for their ability to clear heat, detoxify, cool the blood, and address damp-heat in the intestines. Clinical studies have evaluated this combination, often in conjunction with acupuncture, demonstrating superior efficacy and a more favorable safety profile compared to conventional treatments like sulfasalazine for managing intestinal inflammation and symptoms such as bloody stool and diarrhea.
- Other names
- Baitouweng Kushen decoctionBai Tou Weng and Ku Shen decoctionBai Tou Weng Tang + Ku Shen Tang
02
Targets
BUB1 (BUB1 mitotic checkpoint serine/threonine kinase)STAT3 (Signal Transducer and Activator of Transcription 3)
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