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Baihe Ningshen Granules
- Development stage
- Unknown
- Lead developer
- Beijing Anding Hospital
- Administration
- Oral
01
Overview
Baihe Ningshen Granules is a Traditional Chinese Medicine (TCM) botanical drug product developed by Beijing Anding Hospital, Capital Medical University. It is formulated as granules for oral administration and is specifically investigated for the treatment of mild to moderate generalized anxiety disorder (GAD). The preparation is based on TCM principles of 'calming the spirit' (Ningshen) and 'nourishing the heart,' typically utilizing ingredients like Lily bulb (*Lilium brownii*; Baihe). Clinical research, including randomized controlled trials (e.g., ChiCTR2400087397), is focused on evaluating its efficacy and safety as a potential alternative or adjunctive therapy to conventional anxiolytics, while also exploring its underlying biological mechanisms.
- Brand names
- Baihe Ningshen Granules
- Other names
- 百合宁神颗粒
02
Targets
ADORA1 (Adenosine receptor A1 subtype)NF-κBHTR2A (Serotonin receptor 5-HT2A)GABAA (Gamma-aminobutyric acid receptor)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))
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