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Baihu Decoction
- Development stage
- Phase 1
- Lead developer
- Jiangsu Hospital of Integrated Traditional Chinese and Western Medicine
- Administration
- Oral
01
Overview
Baihu Decoction is a classic Traditional Chinese Medicine (TCM) formula originating from the *Shanghan Lun* (Treatise on Cold Damage). It is traditionally indicated for clearing 'Qi-level heat' and draining fire, typically characterized by high fever, intense thirst, profuse sweating, and a surging pulse. The formula is composed of four primary ingredients: Gypsum fibrosum (Shi Gao), Anemarrhena asphodeloides (Zhi Mu), Glycyrrhiza uralensis (Gan Cao), and non-glutinous rice (Geng Mi). In modern clinical research, it is being investigated for its potential neuroprotective and anti-inflammatory effects in conditions such as acute cerebral infarction, particularly when presenting with 'fiery-heat syndrome.' It is often utilized as a component of the DAIRIES program (Decoction and Acupuncture combined with Immunomodulatory Rehabilitation Regimen) to mitigate neurological impairment and improve patient prognosis.
- Other names
- Baihu TangWhite Tiger Decoction
02
Targets
SDH (Mitochondrial electron transport chain complex II)IL1B (Interleukin-1 beta)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)SUCNR1 (Succinate receptor 1)TLR4 (Toll-like receptor 4)
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