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Baizhi extract is a concentrated preparation of the dried root of *Angelica dahurica* (also known as Bai Zhi or Dahurian Angelica Root), a medicinal plant widely used in Traditional Chinese Medicine (TCM)[3][13]. The extract contains a complex mixture of bioactive compounds, including coumarins (e.g., imperatorin, isoimperatorin, oxypeucedanin, xanthotoxol, bergapten, cnidilin), furanocoumarins, volatile oils, and other phytochemicals[2][6][13]. Pharmacological studies indicate that baizhi extract has anti-inflammatory, analgesic, anti-microbial, anti-tumor, anti-oxidation, cardiovascular, neuroprotective, hepatoprotective, and skin-protective activities[3][13]. Its primary mechanisms are attributed to the coumarin and furanocoumarin content, influencing targets involved in inflammation and possibly modulating drug metabolism by inhibiting cytochrome P450 enzymes, especially the CYP3A subfamily[6]. Baizhi extract is most commonly used in TCM to treat headaches, nasal congestion, pain, abscesses, and swelling, and is usually administered as a granule, powder, or tincture dissolved in water or other liquids[1][4][7].
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