Drug intelligence / Profile preview

balance

Development stage
Phase 4
Lead developer
Fresenius Medical Care
Modality
Small Molecules
Administration
Peritoneal
01

Overview

Balance is a pH-neutral peritoneal dialysis solution developed by Fresenius Medical Care. It is designed to provide a more biocompatible alternative to conventional acidic dialysis fluids by utilizing a dual-chamber system that separates glucose from the buffer during sterilization, thereby minimizing the formation of glucose degradation products (GDPs). Upon mixing before administration, the solution achieves a physiological pH. It contains glucose as an osmotic agent to remove excess water and toxins from the blood across the peritoneal membrane, along with essential electrolytes and a lactate buffer to correct metabolic acidosis in patients with chronic kidney failure.

Brand names
balancestay-safe balancesleep-safe balance
Other names
peritoneal dialysis solution

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