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balanol analog 2

Development stage
Unknown
Modality
Small Molecules
01

Overview

Balanol Analog 2 is a synthetic small molecule and an experimental analog of the natural product balanol. It belongs to the class of benzophenones and is structurally related to ATP, with distinct regions mimicking adenine, ribose, and phosphate groups. Balanol Analog 2 acts as a potent inhibitor of protein kinases—specifically targeting serine/threonine kinases such as cyclic AMP-dependent protein kinase (PKA) more selectively than protein kinase C (PKC). The compound has been used in structural biology studies to probe specificity determinants and conformational flexibility in kinase active sites. It is not approved for clinical use and remains an experimental tool compound for research on kinase inhibition[1][3][9].

Other names
3-[(4-hydroxybenzoyl)amino]azepan-4-yl 4-(2-hydroxybenzoyl)benzoate
02

Targets

PKA (Cyclic amp-dependent protein kinase)PKC (Protein kinase C family)

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