Drug intelligence / Profile preview

Balsoprim

Development stage
Unknown
Lead developer
Laboratorio Farmaceutico SIT
Modality
Small Molecules
Administration
Oral
01

Overview

**Balsoprim** is a prescription fixed-dose oral suspension containing sulfamethoxazole, trimethoprim, and bromhexine hydrochloride. Sulfamethoxazole and trimethoprim sequentially inhibit bacterial folate synthesis, providing antibacterial activity, while bromhexine is a mucolytic that promotes clearance of airway secretions. In Spain, it is indicated for acute exacerbation of chronic bronchitis in patients without risk factors when mucolytic action is required, and for acute otitis media and acute bacterial sinusitis when usual first-line antibacterial agents are inappropriate. The marketed product is an oral suspension containing 26.6 mg/mL sulfamethoxazole, 5.4 mg/mL trimethoprim, and 0.5 mg/mL bromhexine hydrochloride. ([cima.aemps.es](https://cima.aemps.es/cima/dochtml/p/49391/P_49391.html))

Brand names
Balsoprim
Other names
sulfamethoxazole + trimethoprim + bromhexine hydrochloride
02

Targets

DHFR (Dihydrofolate reductase)DHPS (Dihydropteroate synthase)

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