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Banxia Baizhu Tianma formula

Development stage: Preclinical
Lead developer: Sichuan Guangda Pharmaceutical
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Banxia Baizhu Tianma formula (also known as Banxia Baizhu Tianma decoction or Tang) is a classic traditional Chinese medicine (TCM) herbal formula. It is traditionally used to treat vertigo, dizziness, and headache associated with wind-phlegm syndrome and spleen deficiency. The formula typically consists of several herbal ingredients, including *Pinellia ternata* (Banxia), *Atractylodes macrocephala* (Baizhu), and *Gastrodia elata* (Tianma). In clinical trials, such as those sponsored by Shijiazhuang Hospital of Traditional Chinese Medicine, a granule/particle formulation of the formula (manufactured by Shineway Pharmaceutical) is being evaluated for the treatment of acute vertigo episodes associated with posterior circulation ischemia.

Other names: Banxia Baizhu Tianma decoctionBanxia Baizhu Tianma formula granulesBanxia Baizhu Tianma formula particlesBanxia Baizhu Tianma TangBanxia Baizhu Tianma Tang granulesSemipinellia and Atractylodes DecoctionSemipinellia and Atractylodes Decoction Granules

Targets

NOS3 (eNOS)ACE (Angiotensin Converting Enzyme)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)EGFR T790M (Epidermal growth factor receptor T790M mutant)

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