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Bao Yuan Gao

Development stage: Unknown
Lead developer: Chang Gung Memorial Hospital
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Topical

Overview

Bao Yuan Gao is a traditional Chinese herbal ointment formulated for the prevention and management of acute radiation dermatitis (RD). It is primarily investigated for use in patients with head and neck cancer undergoing radiotherapy, where it is applied topically to mitigate skin damage. The ointment possesses significant anti-inflammatory properties, which help to reduce erythema, maintain skin moisture, and decrease melanin deposition and pain associated with high-dose radiation exposure. Clinical studies have indicated that Bao Yuan Gao may provide superior skin-protective effects compared to standard non-steroidal topical agents like Calendula cream, potentially reducing the need for nutritional support by managing treatment-related morbidity.

Brand names: Bao Yuan Gao
Other names: Bao-Yuan-Gao

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