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Base Cream refers to the topical vehicle formulation used as a comparator in clinical research conducted by Wright State University, specifically in studies targeting photosensitivity. In these trials, such as those investigating the effects of topical imipramine on ultraviolet B (UVB) induced microvesicle particle release and erythema, the base cream serves as a placebo control. It is designed to be pharmacologically inactive, allowing researchers to isolate the therapeutic effects of the active ingredient from the physical properties of the cream's application, such as skin hydration or barrier protection.
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