Drug intelligence / Profile preview

Basil

Development stage
Unknown
Lead developer
Guangdong Provincial Hospital of Traditional Chinese Medicine
Administration
Oral, Subcutaneous, Intradermal, Topical
01

Overview

Basil (*Ocimum basilicum*), referred to in traditional Chinese medicine as Luóle (罗勒), is being investigated as an adjuvant therapy for patients with non-small cell lung cancer (NSCLC). Clinical research, particularly at institutions like the Guangdong Provincial Hospital of Chinese Medicine, has explored its potential to enhance the efficacy of EGFR tyrosine kinase inhibitors (TKIs) such as gefitinib and erlotinib, as well as standard platinum-based chemotherapy. The therapeutic rationale typically involves the herb's complex mixture of phytochemicals—including eugenol, rosmarinic acid, and flavonoids—which may exert antioxidant, anti-inflammatory, and chemosensitizing effects. In these studies, advanced diagnostic tools like NanoVelcro CTC purification systems are often employed to monitor circulating tumor cells as a biomarker for the herb's clinical impact.

Other names
Ocimum basilicumChinese Herb Basil罗勒
02

Targets

Mpro (3C-like proteinase of SARS-CoV-2)CYP2B6 (Cytochrome P450 2B6)

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