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basil oil

Development stage: Phase 3
Lead developer: Iran University of Medical Sciences
Administration: Topical

Overview

Basil oil is a traditional herbal remedy derived from the Ocimum basilicum L. plant, often formulated with sesame oil as a vehicle. It is recognized for its anti-inflammatory, anti-nociceptive (pain-relieving), and anti-oxidative properties, attributed to its rich content of polyphenolic and flavonoid compounds. It is applied topically to manage symptoms of knee osteoarthritis, demonstrating comparable efficacy to diclofenac gel in improving clinical symptoms and functional indicators.

Other names: Ocimum basilicum L. oil

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NF-κBMOR (Mu opioid receptor)IL1B (Interleukin-1 beta)MMP12 (Macrophage Metalloelastase)

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