Drug intelligence / Profile preview

BAT-4706

Development stage: Phase 1
Lead developer: Bio-Thera Solutions
Modality: Monoclonal Antibodies → Antibody-Based Therapeutics
Administration: Intravenous

Overview

BAT4706 is a recombinant, fully human, Fc glycosylation-modified anti-CTLA-4 monoclonal antibody developed by Bio-Thera Solutions for the treatment of solid tumors. It is considered a second-generation CTLA-4 antibody designed to enhance efficacy compared to first-generation therapies. The drug acts as an immune checkpoint inhibitor by targeting cytotoxic T lymphocyte antigen 4 (CTLA-4), thereby promoting T cell activation and antitumor immune responses. Its mechanism of action includes inhibition of CTLA-4, stimulation of T lymphocytes, and induction of antibody-dependent cell cytotoxicity. BAT4706 is currently in phase 1 clinical trials for advanced solid tumors and melanoma, primarily being studied in China[1][2][3].

Other names: Fc-glycosylated recombinant fully humanized anti-CTLA-4 monoclonal antibody injection

Targets

CTLA-4 (Cytotoxic t-lymphocyte–associated protein 4)

Beyond the preview

Go deeper on BAT-4706.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on BAT-4706.

Explore the full profile