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BAT1308 is a recombinant humanized monoclonal antibody that targets the programmed cell death protein 1 (PD-1) receptor. By binding to PD-1, it inhibits its interaction with ligands and downstream signaling pathways, thereby restoring immune function through activation of T cells and promoting T-cell-mediated immune responses against tumor cells. Developed by Bio-Thera Solutions, BAT1308 is being investigated primarily for the treatment of solid tumors, including cervical cancer and endometrial cancer. Its mechanism includes blocking PD-1 to enhance antitumor immunity, with ongoing clinical trials in combination with chemotherapy agents for advanced or recurrent cancers[1][2][4][6].
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