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Battey skin test antigen
- Development stage
- Unknown
- Lead developer
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Intradermal
01
Overview
Battey skin test (BST) antigen is a diagnostic biologic reagent derived from *Mycobacterium intracellulare* (historically known as the Battey bacillus). It is utilized in the differential diagnosis of latent tuberculosis infection (LTBI) to identify cross-reactivity caused by non-tuberculous mycobacteria (NTM). When administered intradermally via the Mantoux method, the antigen elicits a delayed-type hypersensitivity (DTH) response in individuals previously sensitized to the *Mycobacterium avium* complex (MAC). By comparing the induration size of a BST reaction to that of a standard Tuberculin Skin Test (TST), clinicians can better distinguish between true *Mycobacterium tuberculosis* infection and false-positive TST results resulting from environmental mycobacterial exposure.
- Other names
- Battey antigenMycobacterium intracellulare antigenPurified Protein Derivative-Battey
02
Targets
TCR (T cell antigen receptor complex)
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