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BAVU solution
- Development stage
- Phase 1
- Lead developer
- Şişli Etfal Hastanesi
- Modality
- Recombinant Proteins and Enzymes, Small Molecules
- Administration
- Implant
01
Overview
BAVU solution is an experimental tissue preservation and transportation medium specifically developed for use in parathyroid allotransplantation. Developed by researchers at Şişli Hamidiye Etfal Training and Research Hospital, the solution is designed to optimize the viability of parathyroid cells and maintain the functional integrity of calcium-sensing receptors (CaSR) during the cold ischemia period. The name BAVU is an acronym derived from its primary components: Bicarbonate, Albumin, Vitamin E, and University of Wisconsin (UW) solution. It is primarily utilized in clinical research settings to improve the outcomes of parathyroid transplants in patients suffering from permanent hypoparathyroidism, often as a result of parathyroid hyperplasia or surgical complications.
- Other names
- BAVU solution
02
Targets
CaSR (Extracellular calcium-sensing receptor)
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