BAY 79-4980

**BAY 79-4980** was a Bayer investigational, liposome-formulated recombinant coagulation factor VIII product for **severe hemophilia A**. It consisted of sucrose-formulated recombinant factor VIII from Kogenate FS reconstituted with a PEGylated-liposome diluent, producing a non-covalent recombinant FVIII-liposome complex intended to provide more durable bleed protection than conventional recombinant FVIII. It was administered intravenously and evaluated in completed pharmacokinetic studies and a Phase 2 once-weekly prophylaxis study; the Phase 2 study was terminated or withdrawn. ([onlinelibrary.wiley.com](https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1538-7836.2008.02856.x))

Brand names

Kogenate FS liposomeKogenate liposomalNecLip-rFVIII

Other names

Kogenate FS Liposome