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BAY1183345 is a topical lotion developed for the treatment of rosacea, specifically targeting facial redness. It was evaluated in a clinical trial as a sunscreen skin care product to assess its tolerability and effectiveness in reducing facial erythema when applied to the face. The primary outcomes measured included changes in papules, erythema, dryness, telangiectasia, tactile surface roughness, and subjective irritation over up to four weeks. Secondary outcomes included objective measurements of facial redness using spectrophotometry and digital imaging[1][2][3]. The precise mechanism of action is not specified in available sources.
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