BAYH006689

BAYH006689 is a 10% naproxen topical gel developed by Bayer for the treatment of acute soft tissue injuries and musculoskeletal pain. As a non-steroidal anti-inflammatory drug (NSAID), naproxen acts as a small molecule inhibitor of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are responsible for the synthesis of pro-inflammatory prostaglandins. This topical formulation is designed to provide localized relief of minor aches and pains in muscles and joints while potentially reducing the systemic side effects associated with oral NSAID administration. Bayer has evaluated this candidate in Phase 2 clinical trials for sports-related soft tissue injuries of the lower extremities, comparing its efficacy to diclofenac gel and placebo.

Other names

naproxen 10% gelnaproxen topical gel