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Bazhen Granules
- Development stage
- Unknown
- Lead developer
- Lansen Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Bazhen Granules is a traditional Chinese medicine (TCM) product marketed by Lansen Pharmaceutical. It is an oral granule formulation based on the classic Ba Zhen Tang (Eight Treasures Decoction) formula. The product is used in TCM to replenish Qi and nourish blood, specifically targeting "Qi and Blood deficiency" syndrome. This condition is characterized by symptoms such as a sallow or pale complexion, dizziness, palpitations, fatigue, and loss of appetite. As a multi-herb TCM formulation, it contains extracts from eight primary herbs: Panax ginseng, Atractylodes macrocephala, Poria cocos, Glycyrrhiza uralensis, Rehmannia glutinosa, Angelica sinensis, Paeonia lactiflora, and Ligusticum chuanxiong. It is currently approved and marketed in China as a general TCM pharmaceutical.
- Brand names
- Bazhen Granules
- Other names
- 八珍颗粒Ba Zhen Ke LiBa Zhen Tang Granules
02
Targets
STAT3 (Signal Transducer and Activator of Transcription 3)JUN (Transcription factor Jun)VEGFR2 (Vascular endothelial growth factor receptor 2)HIF1A (Hypoxia-inducible factor 1-alpha)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)ESR1 (ERα)TP53 (Cellular Tumor Antigen p53 R175H)MYC (MYC proto-oncogene protein)EGFR T790M (Epidermal growth factor receptor T790M mutant)CASP3 (Caspase-3)
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