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Drug intelligence / Profile preview
BB265
- Development stage
- Preclinical
- Lead developer
- BiomeBank
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
BB265 is a second-generation, co-cultured microbial consortium therapy developed by BiomeBank using its proprietary CONSORTIOME platform. It consists of a defined community of approximately 100 bacterial species selected from BiomeBank's culture collection. The therapy is designed to restore gut microbial ecology and specifically target ulcerative colitis by reducing and consuming hydrogen sulfide, a property linked to clinical remission. BB265 is formulated as a non-immunosuppressive oral therapy and is being prepared for Phase 1b/2a clinical trials.
02
Targets
H2S (Hydrogen sulfide)
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