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BBC-1501 is a small molecule drug developed by Benobio for the treatment of eye diseases, specifically wet age-related macular degeneration (nAMD). It acts as an inhibitor of bromodomain and extraterminal domain proteins (BET), which are epigenetic regulators implicated in inflammation and pathological angiogenesis. The drug is currently in Phase 1 clinical trials to evaluate its safety and tolerability when administered via intravitreal injection in patients with neovascular age-related macular degeneration. Its mechanism targets BET proteins to potentially reduce disease progression associated with abnormal blood vessel growth in the retina[1][2][3][4][5].
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