Drug intelligence / Profile preview

BCG, NeisVac-C, Pediacel, Infanrix, Prevenar-13, Menitorix, Priorix, Rotarix

Development stage
Approved
Lead developer
GSK
Modality
Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Live Attenuated Vaccines → Live Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Whole Inactivated Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Intramuscular, Intradermal, Oral, Subcutaneous
01

Overview

This entry refers to a comprehensive collection of pediatric vaccine products typically utilized in childhood immunization schedules to prevent a wide array of infectious diseases. The list includes **BCG** (Bacillus Calmette-Guérin) for tuberculosis prevention; **NeisVac-C** for protection against *Neisseria meningitidis* serogroup C; **Pediacel**, a pentavalent vaccine covering diphtheria, tetanus, pertussis, poliomyelitis, and *Haemophilus influenzae* type b (Hib); **Infanrix**, a trivalent DTaP vaccine; **Prevenar-13** (PCV13), a 13-valent pneumococcal conjugate vaccine; **Menitorix**, a combined Hib and Meningitis C conjugate vaccine; **Priorix**, a live-attenuated measles, mumps, and rubella (MMR) vaccine; and **Rotarix**, an oral live-attenuated rotavirus vaccine. These products utilize various platforms, including live-attenuated bacterial and viral strains, polysaccharide-protein conjugates, and inactivated toxoids or subunits, to stimulate active immunity and immunological memory against their respective target pathogens.

Brand names
BCGNeisVac-CPediacelInfanrixPrevenar-13Prevenar13Prevenar 13MenitorixPriorixRotarix
Other names
BCG vaccinePCV13PCV-13PCV 13MMR vaccineRotavirus vaccineDTaP-IPV-Hib vaccineHib-MenC vaccineMenC vaccine
02

Targets

Neisseria meningitidis group C capsular polysaccharideDiphtheria toxinPRNP (Cellular Prion Protein)CPS (Streptococcus pneumoniae capsular polysaccharide)

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