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bcg purified protein derivative
- Development stage
- Preclinical
- Lead developer
- Beijing Sanroad Biological Products
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Intradermal
01
Overview
BCG purified protein derivative (BCG-PPD) is a diagnostic skin-test reagent derived from the culture filtrate of *Mycobacterium bovis* BCG. Developed by Sanroad Biological Products, it is primarily used to assess cellular immune reactivity (delayed-type hypersensitivity) in individuals who have received the Bacillus Calmette-Guérin (BCG) vaccine. The reagent is used to evaluate the immune response post-vaccination or to assist in differentiating between reactions caused by *Mycobacterium tuberculosis* infection and those resulting from BCG immunization. Upon intradermal administration, the protein antigens trigger a T-cell mediated response in sensitized individuals, resulting in a measurable induration at the injection site.
- Other names
- BCG-PPD卡介菌纯蛋白衍生物Tuberculin Purified Protein Derivative from BCG
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