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BCMA panCAR
- Development stage
- Preclinical
- Lead developer
- Orna Therapeutics
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
BCMA panCAR is an investigational chimeric antigen receptor (CAR) cell therapy being developed by **Xianbo Biotechnology** (also known as **Simnova Bio**) in collaboration with **Orna Therapeutics**. The therapy utilizes Xianbo's proprietary **panCAR** platform, which is designed to enhance the precision and efficacy of CAR-based treatments. By targeting the **B-cell maturation antigen (BCMA)**, a protein highly expressed on the surface of malignant plasma cells, the therapy aims to treat hematologic malignancies such as multiple myeloma. The partnership with Orna Therapeutics likely leverages Orna's circular RNA (oRNA) technology, which may be used to facilitate the expression of the CAR construct, potentially through *in vivo* delivery or optimized *ex vivo* engineering.
- Other names
- BCMA-targeted panCARBCMA panCAR cell therapy
02
Targets
BCMA (B-cell maturation antigen)
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