Drug intelligence / Profile preview

BCT-194

Development stage
Phase 1
Lead developer
Novartis
Modality
Small Molecules
Administration
Topical
01

Overview

BCT-194 is a small molecule drug developed by Novartis as a topical cream for the treatment of psoriasis. It acts as an inhibitor of p38 mitogen-activated protein kinase (p38 MAPK), a target involved in inflammatory signaling pathways. The drug was investigated primarily for immune system and skin diseases, with clinical trials reaching Phase 1 for psoriasis. Its mechanism of action is to inhibit p38 MAPK, which may reduce inflammation associated with psoriatic lesions. As of the latest updates, development has not progressed beyond early clinical studies and there are no approved indications or brand names associated with this compound[1][2][3].

02

Targets

MAPK14 (p38 mitogen-activated protein kinase alpha)

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