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BDP + AC Plus
- Development stage
- Unknown
- Lead developer
- Chiesi
- Modality
- Small Molecules
- Administration
- Inhalation, Oral
01
Overview
BDP + AC Plus is a clinical trial arm designation used by Chiesi Farmaceutici in pharmacokinetic (PK) studies of inhaled respiratory therapies. In this nomenclature, BDP refers to the inhaled corticosteroid beclomethasone dipropionate; AC refers to the oral co-administration of activated charcoal, which is used to block gastrointestinal absorption and isolate the lung-specific bioavailability of the drug; and Plus denotes the use of the Aerochamber Plus™ spacer device for drug delivery. This specific regimen is typically used as a reference arm in clinical pharmacology trials (such as those for the fixed-dose combination CHF 1535) to evaluate the systemic exposure and pulmonary deposition of beclomethasone dipropionate in pediatric or adult asthmatic populations.
- Other names
- beclomethasone dipropionate + activated charcoal + Aerochamber Plus
02
Targets
GR (Glucocorticoid receptor)
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