Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
becaplermin + bovine collagen matrix
- Development stage
- Unknown
- Lead developer
- Wright Medical Group
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Recombinant Proteins and Enzymes, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Topical, Injectable (for Bone Applications)
01
Overview
**Becaplermin + bovine collagen matrix** is a combination product consisting of recombinant human platelet-derived growth factor BB (becaplermin/rhPDGF-BB) and a matrix made of type I collagen derived from bovine sources. The recombinant growth factor promotes wound and tissue healing by stimulating angiogenesis, recruiting and inducing proliferation of fibroblasts and cells involved in tissue repair, promoting extracellular matrix formation, and enhancing granulation tissue. The **bovine collagen matrix** serves as a delivery scaffold that supports cellular ingrowth and provides structural support while modulating proteases in the wound, protecting growth factors from degradation, releasing them gradually, and accelerating tissue regeneration. This combination is used for applications including chronic wound healing and bone grafting (as in AUGMENT Injectable), especially for diabetic foot ulcers and orthopedic indications such as bone defects or non-unions[1][2][3][6].
- Brand names
- AUGMENT InjectableAUGMENT Bone Graft
- Other names
- recombinant human platelet-derived growth factor BB + bovine type I collagenbecaplermin + bovine type I collagen matrix
02
Targets
PDGFRB (Platelet-derived growth factor receptor beta)
Beyond the preview
Go deeper on becaplermin + bovine collagen matrix.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on becaplermin + bovine collagen matrix.