Drug intelligence / Profile preview

Becaterin

Development stage
Unknown
Modality
Small Molecules
01

Overview

Becaterin is a topical combination medication formulated with a corticosteroid, an aminoglycoside antibiotic, and an azole antifungal agent. It typically contains **betamethasone dipropionate**, **gentamicin sulfate**, and **clotrimazole**. This triple-action therapy is indicated for the treatment of inflammatory skin disorders (dermatoses) that are complicated by, or at risk of, secondary bacterial and fungal infections. Betamethasone provides potent anti-inflammatory, antipruritic, and vasoconstrictive effects by binding to glucocorticoid receptors. Gentamicin sulfate offers broad-spectrum antibacterial activity against susceptible Gram-positive and Gram-negative bacteria by inhibiting protein synthesis. Clotrimazole acts as a broad-spectrum antifungal by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. The drug is commonly marketed in Latin American regions, such as Mexico, for conditions like infected eczema, tinea infections, and various forms of dermatitis.

Brand names
Becaterin
Other names
betamethasone + gentamicin + clotrimazole
02

Targets

CYP (Cytochrome P450 family)Bacterial RibosomeGR (Glucocorticoid receptor)

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