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Drug intelligence / Profile preview
beclometasone + clotrimazole + lidocaine + ofloxacin
- Development stage
- Unknown
- Lead developer
- Med Manor Organics
- Modality
- Small Molecules
- Administration
- Otic
01
Overview
Ercob is a topical combination ear drop formulation containing the corticosteroid beclometasone, the imidazole antifungal clotrimazole, the local anesthetic lidocaine, and the fluoroquinolone antibiotic ofloxacin. Developed by Med Manor Organics, it is indicated for the treatment of various types of ear infections (such as otitis externa and otomycosis) caused by susceptible bacteria and fungi. Within this formulation, ofloxacin provides broad-spectrum antibacterial activity, clotrimazole targets fungal pathogens, beclometasone reduces local inflammation, redness, and swelling, and lidocaine provides rapid relief from ear pain and itching.
- Brand names
- ErcobErcob Ear Drops
- Other names
- beclometasone dipropionate + clotrimazole + lidocaine hydrochloride + ofloxacinbeclomethasone + clotrimazole + lidocaine + ofloxacin
02
Targets
DNA gyraseTopo IV (Bacterial Topoisomerase IV)GR (Glucocorticoid receptor)CYP51A1 (Sterol 14α-demethylase)NaV (Voltage-gated sodium channels)
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