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beclometasone dipropionate + calcipotriene
- Development stage
- Unknown
- Lead developer
- LEO Pharma
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
Beclometasone dipropionate + calcipotriene is a fixed-dose combination topical medication used primarily for the treatment of plaque psoriasis. Beclometasone dipropionate is a synthetic corticosteroid with anti-inflammatory, immunosuppressive, and vasoconstrictive properties. Calcipotriene (also known as calcipotriol) is a synthetic vitamin D3 analog that regulates skin cell production and differentiation. The combination leverages the complementary mechanisms of both agents to improve efficacy and convenience over monotherapy, with once-daily application recommended for up to four weeks. The product should not be used on the face, groin, or axillae and should be discontinued when control is achieved[5].
- Other names
- BDP + AC Plus
02
Targets
GR (Glucocorticoid receptor)VDR (Vitamin D receptor)
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