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beclomethasone + lidocaine + phenylephrine
- Development stage
- Unknown
- Lead developer
- Rebrace Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Topical, Rectal
01
Overview
Pilohenz ANO Cream is a topical combination therapy developed by Rebrace Pharmaceuticals for the treatment of hemorrhoids (piles) and anal fissures. The formulation contains three active pharmaceutical ingredients: beclomethasone dipropionate, a potent corticosteroid that reduces inflammation, swelling, and itching; phenylephrine hydrochloride, a sympathomimetic amine that acts as a vasoconstrictor to shrink swollen blood vessels in the anorectal area; and lidocaine (lignocaine) hydrochloride, a local anesthetic that provides rapid relief from pain and discomfort. The cream is designed for topical application to the affected area to manage symptoms associated with inflammatory anorectal conditions.
- Brand names
- Pilohenz ANO Cream
- Other names
- beclomethasone dipropionate + lidocaine hydrochloride + phenylephrine hydrochloridebeclomethasone dipropionate + lignocaine hydrochloride + phenylephrine hydrochloride
02
Targets
GR (Glucocorticoid receptor)ADRA1A (α1A)NaV (Voltage-gated sodium channels)
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