Drug intelligence / Profile preview

beclomethasone dipropionate + salmeterol

Development stage
Unknown
Lead developer
GSK
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Inhalation
01

Overview

Beclomethasone dipropionate + salmeterol is a fixed-dose combination inhaled medication used primarily for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD). It combines two active ingredients: - Beclomethasone dipropionate, an inhaled corticosteroid that exerts anti-inflammatory effects by suppressing the activity of various inflammatory cells and mediators in the airways, thereby reducing airway inflammation. - Salmeterol, a long-acting beta2-adrenergic agonist (LABA) that acts as a bronchodilator by stimulating beta2 receptors in bronchial smooth muscle, leading to prolonged relaxation of airway muscles and improved airflow. This combination is indicated for patients whose asthma or COPD is not adequately controlled with inhaled corticosteroids alone. The use of both agents together provides synergistic benefits—reducing inflammation while also improving bronchodilation and symptom control[5][4][7].

Other names
beclomethasone + salmeterolbeclomethasone dipropionate + salmeterol
02

Targets

GR (Glucocorticoid receptor)ADRB2 (β2)

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