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This combination is a dietary supplement formulation designed to enhance nitric oxide (NO) bioavailability through two distinct physiological pathways. Beet root extract serves as a rich source of inorganic nitrates, which are reduced to nitrites by commensal oral bacteria and subsequently converted to nitric oxide in the acidic environment of the stomach or under hypoxic conditions in tissues. L-arginine acts as the primary substrate for the enzyme nitric oxide synthase (NOS), which catalyzes the production of NO and L-citrulline. L-citrulline is included to bypass first-pass metabolism in the liver, effectively increasing systemic L-arginine levels more efficiently than arginine supplementation alone. The synergistic effect is intended to promote vasodilation, improve endothelial function, and enhance exercise performance and cardiovascular health.
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