Drug intelligence / Profile preview

Beijing Normal Univ. PSMA compound 17

Development stage
Unknown
Lead developer
Beijing Normal University
01

Overview

Beijing Normal Univ. PSMA compound 17: sourced facts only. name: "Among them, ligands 17, 18, and 21-24 bearing the squaramic acid moiety proved to be potent PSMA inhibitors, with Ki values ranging from 0.40 to 2.49 nM, which are comparable or higher in inhibitory potency compared to previously reported glutamate-urea-based inhibitors." [PMID:37161996]; target: "Among them, ligands 17, 18, and 21-24 bearing the squaramic acid moiety proved to be potent PSMA inhibitors, with Ki values ranging from 0.40 to 2.49 nM, which are comparable or higher in inhibitory potency compared to previously reported glutamate-urea-based inhibitors." [PMID:37161996]; developer: "Key Laboratory of Radiopharmaceuticals, Ministry of Education, Beijing Normal University, Beijing 100875, China." [PMID:37161996]

02

Targets

PSMA (Prostate-specific membrane antigen)

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